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Vitamin D deficiency myopathy (often known as osteomalic myopathy as a result of interplay between vitamin D and calcium) results in muscle weakness, predominantly of the proximal muscles; with muscle biopsy displaying abnormal glycogen accumulation, atrophy of sort II (fast-twitch/glycolytic) muscle fibres, and diminished calcium uptake by the sarcoplasmic reticulum (wanted for muscle contraction). Exercise-induced, electrically silent, muscle cramping and stiffness (transient muscle contractures or "pseudomyotonia") are seen not solely in GSD sorts V, VII, IXd, X, XI, XII, and XIII, but in addition in Brody illness, Rippling muscle illness varieties 1 and 2, and CAV3-related hyperCKemia (Elevated serum creatine phosphokinase).<br>
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